I have been publishing articles on the web since 2008 — and tinkering with other websites (e.g. Geocities) since well before that. Over time, the size of each webpage has exploded. Going forward, you'll be able to view my website by only retrieving one file — this one — and I endeavour to keep it to a manageable size.
For testing the layout, I only test for support with 1024x768 on latest Firefox and using the iPhone 6 layout on Chrome. Whitespace behavior is specified by me in the document. If I want pixel perfect display, I'll likely use an image map.
If the display is broken in your environment, please let me know. Untested but I'd like the website to perform well in screenreaders as well. Also let me know if this isn't the case.